Estrogen Receptor Alpha Gene Polymorphisms and Stroke
نویسندگان
چکیده
منابع مشابه
Polymorphisms in the estrogen receptor alpha gene and mammographic density.
The presence of the PvuII or the XbaI polymorphism in the estrogen receptor alpha gene (ESR1, 6q25) has been related to breast cancer risk; however, results are not fully consistent. To further elucidate this relation, we examined these polymorphisms in relation with mammographic density, a measure of dense tissue in the breast, which is strongly associated with breast cancer risk. For this stu...
متن کاملAssociation of estrogen receptor-alpha gene polymorphisms with stroke risk in patients with metabolic syndrome.
OBJECTIVE The vascular protective effects of estrogens are mediated by their binding to the two known estrogen receptors. In this study, we examine the association of stroke with two common polymorphisms of the ESR1 gene in patients with metabolic syndrome. MATERIALS AND METHODS DNA from 130 patients hospitalized for ischemic stroke and 240 healthy controls were genotyped for ESR1 PvuII and X...
متن کاملAssociation between estrogen receptor-alpha gene PvuII and XbaI polymorphisms and osteoarthritis risk: a meta-analysis.
Estrogen receptor-alpha (ER-α) gene PvuII (T/C) and XbaI (A/G) polymorphisms have been hypothesized to be associated with osteoarthritis (OA) risk by several epidemiological studies, however, the available results were inconclusive and conflicting. We conducted a meta-analysis of 10 case-control studies that included 3328 osteoarthritis cases and 6390 case-free controls. We assessed the strengt...
متن کاملAssociation between polymorphisms in the estrogen receptor alpha gene and osteoarthritis susceptibility: a meta-analysis
BACKGROUND Osteoarthritis (OA) is a common chronic disease of the joints. Genetic factors may play a role in its development, and polymorphisms in the estrogen receptor alpha gene (ERα) have been associated with OA. However, previous studies into this relationship have reported inconsistent results, so we aimed to systematically review the association between ERα polymorphisms and OA susceptibi...
متن کاملEstrogen Receptor Alpha (ESR1) Gene Polymorphisms in Pre-eclamptic Saudi Patients
OBJECTIVES Pre-eclampsia causes maternal mortality worldwide. Estrogen receptor alpha (ESR1) gene polymorphisms were responsible for cardiovascular diseases. This case control study was conducted to investigate whether 2 polymorphic genes of ESR1 are associated with pre-eclampsia among Saudi women in Madina city, Saudi Arabia. METHODS Blood samples from 97 pre-eclamptic and 94 healthy pregnan...
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ژورنال
عنوان ژورنال: Cerebrovascular Diseases
سال: 2008
ISSN: 1421-9786,1015-9770
DOI: 10.1159/000151591